4-Methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine CAS 4893-92-9
| CAS No. | 4893-92-9 |
| Molecular Formula | C8H7N3O2 |
| Molecular Weight | 177.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 4893-92-9), molecular formula C8H7N3O2 and molecular weight 177.16 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine (C8H7N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 177.16 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3O2 |
| Molecular Weight | 177.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 6-Methyl-5-nitro-7H-pyrrolo[2,3-b]pyridine (CAS 1000340-19-1)
- 5-Nitro-1H-indol-6-amine (CAS 1000343-12-3)
- 4-Methyl-7-nitro-1H-benzo[d]imidazole (CAS 101420-63-7)
- 6-Methyl-4-nitro-1H-benzo[d]imidazole (CAS 101420-64-8)
- 3-Methyl-7-nitro-1H-indazole (CAS 101420-66-0)
- 4-Methyl-5-nitro-1H-indazole (CAS 101420-67-1)
- 4-Methyl-7-nitro-1H-indazole (CAS 104103-06-2)
- 5-Methyl-7-nitro-1H-indazole (CAS 113302-88-8)
Recommended Standards
- 4-Methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione (CAS 80708-25-4)
- 4-Methyl-6-nitro-1H-benzo[d]imidazole (CAS 861600-96-6)
- 4-Methoxyisoindoline-1,3-dione (CAS 41709-83-5)
- 4-Methyl-6-nitro-1H-indazole (CAS 885520-77-4)
- N-Butyl-1-naphthamide (CAS 54751-78-9)
- 2-(5-Bromo-2-fluoro-3-methylphenyl)propan-2-ol (CAS 1522984-26-4)
- 1,2,3,5-Tetrahydro-4H-cyclopenta[c]quinolin-4-one (CAS 4514-03-8)
- N-(4-Acetylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 627044-94-4)
- 3-(Isopentylamino)benzonitrile (CAS 1019621-44-3)
- (4-(5-Amino-1,3,4-thiadiazol-2-yl)phenyl)boronicacid (CAS 957034-52-5)
- Argatroban Impurity 129 (CAS CATO-C4X-1007129)
- 3-(3’,4’-Dimethoxyphenyl)-7-methoxycoumarin (CAS 127073-90-9)
- [(4-chlorophenyl)methyl]hydrazine (CAS 25198-45-2)
- Exenatide Acetate (CAS 141732-76-5)
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