1-(Furan-2-ylmethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one CAS 489397-64-0
| CAS No. | 489397-64-0 |
| Molecular Formula | C23H18N2O7 |
| Molecular Weight | 434.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Furan-2-ylmethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one.
CATO supplies 1-(Furan-2-ylmethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 489397-64-0), a certified reference material (molecular formula C23H18N2O7, MW 434.40 g/mol) for analytical method development and quality control.
The molecular framework of 1-(Furan-2-ylmethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (C23H18N2O7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Furan-2-ylmethyl)-3-hydroxy-4-(4-methoxybenzoyl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H18N2O7 |
| Molecular Weight | 434.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Furan Standards
- Methyl 2-(2-((5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 332867-75-1)
- 2-((3-(Furan-2-ylmethyl)-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 878683-66-0)
- 1-(Furan-2-ylmethyl)-2-imino-8-methyl-5-oxo-N-((tetrahydrofuran-2-yl)methyl)-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide (CAS 510760-81-3)
- 2-((5-(Furan-2-yl)-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 886920-64-5)
- 1-(Furan-2-ylmethyl)-2-imino-10-methyl-3-(4-methylpiperazine-1-carbonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 510760-93-7)
- 1-(Furan-2-ylmethyl)-2-imino-3-(phenylsulfonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606951-74-0)
- 3-(Furan-2-yl)-6-(4-(styrylsulfonyl)piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1060345-23-4)
- N-(4-(2-((4-(Furan-2-yl)thiazol-2-yl)amino)-2-oxoethyl)thiazol-2-yl)-3-phenylacrylamide (CAS 1207061-65-1)
Recommended Standards
- PEG3-bis-(ethyl phosphonate) (CAS 160625-24-1)
- 2-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-oxoethyl 2-(furan-2-yl)quinoline-4-carboxylate (CAS 522624-94-8)
- (R)-Bicalutamide-d4 (CAS 1217826-87-3)
- 2-Nitro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide (CAS 349615-08-3)
- N1-isobutyl-N2-methyloxalamide (CAS 69433-41-6)
- Methyl (2-carbamoylphenyl)glycinate (CAS 88267-57-6)
- 2-(2-((Benzyl(cyclopropyl)amino)methyl)piperidin-1-yl)acetic acid (CAS 1353968-51-0)
- 5-Bromo-1H-pyrrolo[2,3-b]pyridin-6-ol (CAS 1190316-82-5)
- 2-(((5-Chloro-2,4-dimethoxyphenyl)amino)methyl)-6-ethoxyphenol (CAS 1232782-30-7)
- 2-Phenylpyrazolo[1,5-c]quinazolin-5-amine (CAS 1416438-94-2)
- Methyl 3-amino-4-hydroxy-5-(trifluoromethyl)benzoate (CAS 946121-37-5)
- 2-Fluoro-4-hydroxybenzaldehyde (CAS 348-27-6)
- 4-Amino-4-methylpentan-2-ol (CAS 4404-98-2)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
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