4-Hydroxy-1,5-naphthyridine-3-carboxylicacid CAS 4901-93-3
| CAS No. | 4901-93-3 |
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-1,5-naphthyridine-3-carboxylicacid (C9H6N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-Hydroxy-1,5-naphthyridine-3-carboxylicacid (CAS 4901-93-3), a certified reference material (molecular formula C9H6N2O3, MW 190.16 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
- 8-Hydroxy-1,7-naphthyridine-5-carboxylic acid (CAS 1421473-07-5)
- 2-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 17326-26-0)
- 2-Hydroxy-1,8-naphthyridine-4-carboxylic acid (CAS 1823901-95-6)
- 1-Hydroxy-2,7-naphthyridine-3-carboxylic acid (CAS 42285-31-4)
- 4-Hydroxy-1,5-naphthyridine-3-carboxylic Acid (CAS 53512-10-0)
- 4-Hydroxy-1,8-naphthyridine-3-carboxylic acid (CAS 342623-43-2)
- 4-Hydroxy-3-cinnolinecarboxylic acid (CAS 53512-17-7)
- 4-Hydroxy-6-nitroquinoline (CAS 23432-42-0)
Recommended Standards
- 4-Formyl-1h-indazole-3-carboxylic acid (CAS 885519-90-4)
- 4,5-Dihydro[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium-3-olate (CAS 257869-90-2)
- 4-(4-Nitro-1h-pyrazol-3-yl)pyridine (CAS 27116-83-2)
- 4-Nitro-3-phenylisoxazole (CAS 31301-41-4)
- 41862-14-0 6-Amino-1,3-dipropyl-1H-pyrimidine-2,4-dione 6-Amino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione 6-Amino-1,3-dipropyluracil (CAS 41862-14-0)
- Quinolin-8-yl (2-methoxyphenyl)carbamate (CAS 20842-56-2)
- 1-Bromo-2-nitro-4-(trichloromethoxy)benzene (CAS 1417567-84-0)
- Methyl 4-(4-(methylthio)phenyl)-4-oxobutanoate (CAS 108960-07-2)
- tert-Butyl ((6-(dipropylamino)pyridin-3-yl)methyl)carbamate (CAS 1355217-58-1)
- 6-(4-Piperidinyl)quinoline (CAS 1020277-40-0)
- tert-Butyl 4-(3-aminoazetidin-1-yl)piperidine-1-carboxylate dihydrochloride (CAS 1179361-59-1)
- 3-Chloro-1-ethyl-5,6,7,8-tetrahydroisoquinoline-4-carboxamide (CAS 361534-80-7)
- Pyrazolo[1,5-α]pyrimidin-7(1H)-one (CAS 57489-79-9)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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