2-Phenyl-5-(trifluoromethyl)-1H-indole CAS 491601-38-8

Purity 97%+In StockPharmaceutical Standards
CAS No.491601-38-8
Molecular FormulaC15H10F3N
Molecular Weight261.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Phenyl-5-(trifluoromethyl)-1H-indole CAS 491601-38-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 261.24 g/mol gives 2-Phenyl-5-(trifluoromethyl)-1H-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Phenyl-5-(trifluoromethyl)-1H-indole (CAS 491601-38-8), molecular formula C15H10F3N and molecular weight 261.24 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Phenyl-5-(trifluoromethyl)-1H-indole (C15H10F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 261.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Phenyl-5-(trifluoromethyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H10F3N
Molecular Weight261.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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