2-Bromo-3,5-difluoroanisole CAS 491852-44-9
| CAS No. | 491852-44-9 |
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-3,5-difluoroanisole is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Bromo-3,5-difluoroanisole (CAS 491852-44-9), a certified reference material (molecular formula C7H5BrF2O, MW 223.01 g/mol) for analytical method development and quality control.
Based on its molecular formula C7H5BrF2O, 2-Bromo-3,5-difluoroanisole contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,6-difluoroanisole (CAS 104197-14-0)
- 2-Bromo-1,1,1,3-tetrafluoro-3-methylbutane (CAS 1099598-06-7)
- 3-Bromo-4,5-difluorobenzyl alcohol (CAS 1143502-71-9)
- (3-Bromo-2,5-difluorophenyl)methanol (CAS 1159186-56-7)
- 2-Bromo-1,4-difluoro-3-methoxybenzene (CAS 1208076-11-2)
- (2-Bromo-3,5-difluorophenyl)methanol (CAS 1256081-83-0)
- (4-Bromo-3,5-difluorophenyl)methanol (CAS 1256276-36-4)
- 3-Bromo-2-(difluoromethyl)phenol (CAS 1261477-43-3)
Recommended Standards
- 2-Bromo-3,4-difluoroanisole (CAS 935285-66-8)
- 2-Bromo-4,5-difluorobenzyl alcohol (CAS 476620-55-0)
- 2,6-Dichloro-4-(difluoromethyl)nicotinonitrile (CAS 960293-93-0)
- 2-Bromo-4,6-difluoroanisole (CAS 202865-59-6)
- CAS 287100-89-4 (CAS 287100-89-4)
- 1-(1-(3,4-Dimethoxyphenyl)-3-hydroxypropyl)thiourea (CAS 860612-20-0)
- 1,4-Bis(5-(trifluoromethyl)pyridin-2-yl)piperazine (CAS 131136-84-0)
- 6,7-Dimethoxy-2-methyl-1-(2,3,4-trichlorophenethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 63937-61-1)
- 3-(2h-Indazol-3-ylformamido)propanoic acid (CAS 1019110-35-0)
- 5-Nitro-1H-indazol-6-ol (CAS 1082041-56-2)
- Methyl 1-benzyl-1H-1,2,3-triazole-5-carboxylate (CAS 342894-43-3)
- (S)-2-amino-N-benzyl-3-(1H-indol-3-yl)propanamide hydrochloride (CAS 159098-64-3)
- 2-Chloro-1,3-thiazole-5-carbonyl chloride (CAS 148637-74-5)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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