N-(2,4-Difluorophenyl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]acetamide CAS 491867-64-2
| CAS No. | 491867-64-2 |
| Molecular Formula | C16H17F2N5O |
| Molecular Weight | 333.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2,4-Difluorophenyl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2,4-Difluorophenyl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]acetamide (CAS 491867-64-2) is a high-purity analytical reference standard with the molecular formula C16H17F2N5O and a molecular weight of 333.34 g/mol.
Structurally, N-(2,4-Difluorophenyl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]acetamide (C16H17F2N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 333.34 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,4-Difluorophenyl)-2-[4-(pyrimidin-2-yl)piperazin-1-yl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17F2N5O |
| Molecular Weight | 333.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- 3-(2,4-Difluorophenyl)-1-[4-(morpholin-4-yl)phenyl]urea (CAS 866156-01-6)
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- (3,4-Difluorophenyl)(4-((2-ethyl-1H-imidazol-1-yl)methyl)piperidin-1-yl)methanone (CAS 1351595-58-8)
- (4E)-2-(2,6-Difluorophenyl)-4-[1-(dimethylamino)-2-(1H-1,2,4-triazol-1-yl)ethylidene]-4,5-dihydro-1,3-oxazol-5-one (CAS 866010-31-3)
- (R)-3-(3,5-Difluorophenyl)-3-(1-(methylsulfonyl)piperidin-4-yl)propan-1-ol (CAS 718610-74-3)
- (7-(2,5-Difluorophenyl)-1,4-thiazepan-4-yl)(phenyl)methanone (CAS 1705437-88-2)
- (2,4-Difluorophenyl)(2-(thiomorpholinomethyl)phenyl)methanone (CAS 898782-41-7)
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Recommended Standards
- N-((1-(4-Fluorophenyl)-1H-tetrazol-5-yl)methyl)benzenesulfonamide (CAS 941964-37-0)
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- Methyl 6-(furan-2-yl)-3-methyl-1-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 832746-65-3)
- N-(3-(1H-Benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)-3-methoxybenzamide (CAS 825616-22-6)
- Pyridoxine-D5 (CAS 688302-31-0)
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- S-2238 (CAS 115388-96-0)
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- Valproate EP Impurity I (CAS 13310-75-3)
- Allyl 3-ethoxy-4-((2-fluorobenzyl)oxy)-5-iodobenzoate (CAS 1706439-35-1)
- 3-(chloromethyl)-5-(4-methyl-1,3-thiazol-5-yl)-1,2,4-oxadiazole (CAS 1152504-93-2)
- (S)-1-(2,6-Diethylphenyl)-3-(1-hydroxy-3-methylbutan-2-yl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V) (CAS 2248771-37-9)
- 3-((Diisopropylamino)methyl)-4-methoxybenzaldehyde (CAS 881040-95-5)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
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