TCS PIM-1 1, 97%, a potent and selective ATP-competitive Pim-1 kianse inhibitor CAS 491871-58-0
| CAS No. | 491871-58-0 |
| Molecular Formula | C18H11BrN2O2 |
| Molecular Weight | 367.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
TCS PIM-1 1, 97%, a potent and selective ATP-competitive Pim-1 kianse inhibitor (CAS 491871-58-0) is a high-purity analytical reference standard with the molecular formula C18H11BrN2O2 and a molecular weight of 367.20 g/mol.
TCS PIM-1 1, 97%, a potent and selective ATP-competitive Pim-1 kianse inhibitor (C18H11BrN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures TCS PIM-1 1, 97%, a potent and selective ATP-competitive Pim-1 kianse inhibitor under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11BrN2O2 |
| Molecular Weight | 367.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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