Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate CAS 494767-21-4
| CAS No. | 494767-21-4 |
| Molecular Formula | C12H17ClN2O3 |
| Molecular Weight | 272.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate.
Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate (CAS 494767-21-4) is a high-purity analytical reference standard with the molecular formula C12H17ClN2O3 and a molecular weight of 272.73 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 272.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17ClN2O3 |
| Molecular Weight | 272.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (2-((2-chloropyrimidin-4-yl)amino)ethyl)carbamate (CAS 849751-45-7)
- tert-Butyl (6-chloro-5-methoxy-4-methylpyridin-3-yl)carbamate (CAS 2201101-36-0)
- N-(4-Chlorophenyl)-2,3-dihydro-1H-indole-1-carboxamide (CAS 89731-81-7)
- Bedaquiline Impurity 9 (CAS 791633-38-0)
- 2-(Adamantan-1-ylformamido)acetic acid (CAS 21241-41-8)
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- 3-(Bicyclo[2.2.1]heptan-2-yl)-4-methyl-1h-pyrazol-5-amine (CAS 1325760-59-5)
- 3-Chlorophenyl (2E)-3-(6-bromo-2H-1,3-benzodioxol-5-yl)prop-2-enoate (CAS 478259-32-4)
- Demephion (O&S) (CAS 8065-62-1)
- 2-[Ethyl-(3-trifluoromethyl-benzyl)-amino]-ethanol (CAS 1250252-14-2)
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- Dehydroabietic Acid (CAS 1740-19-8)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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