5-Bromo-2-(tetrahydropyran-4-yloxy)pyridine CAS 494772-07-5
| CAS No. | 494772-07-5 |
| Molecular Formula | C10H12BrNO2 |
| Molecular Weight | 258.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-2-(tetrahydropyran-4-yloxy)pyridine (CAS 494772-07-5) is a high-purity analytical reference standard with the molecular formula C10H12BrNO2 and a molecular weight of 258.11 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 5-Bromo-2-(tetrahydropyran-4-yloxy)pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 258.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-2-(tetrahydropyran-4-yloxy)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO2 |
| Molecular Weight | 258.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Bromo-N-(2-methoxyethyl)benzamide (CAS 95086-95-6)
- 5-Bromo-2-propoxybenzamide (CAS 882093-01-8)
- 4-Bromo-3-dimethylaminobenzoic acid methyl ester (CAS 2091860-59-0)
- 5-Bromo-N-cyclopentylfuran-2-carboxamide (CAS 545366-68-5)
- 2-Bromo-5-chloro-N-isopropyl-4-methylbenzenesulfonamide (CAS 1246821-20-4)
- 3-Bromo-2-(2-methoxyethoxy)phenylboronic acid (CAS 2377606-17-0)
- DCMB MALEATE (CAS 77086-19-2)
- 2-(Cyclobutylamino)isonicotinic acid (CAS 1251225-65-6)
- 4-(3-Fluorophenyl)thiazole-2-carboxylic acid (CAS 886367-31-3)
- N-(1-oxo-5z,8z,11z,14z-eicosatetraenyl)-l-alanine (CAS 401941-73-9)
- tert-Butyl 4-(hydroxymethyl)-4-methoxypiperidine-1-carboxylate (CAS 239073-94-0)
- 6-(2-Hydroxyethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 712319-12-5)
- 7-Bromo-2-(pyridin-3-yl)-4H-chromen-4-one (CAS 1920-52-1)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com