1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline,HCl CAS 495-59-0
| CAS No. | 495-59-0 |
| Molecular Formula | C11H12N2 |
| Molecular Weight | 172.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline,HCl is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 172.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline,HCl (CAS 495-59-0), molecular formula C11H12N2 and molecular weight 172.23 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12N2 |
| Molecular Weight | 172.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related tetrahydropyrrolo Standards
- Tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-3(2H)-one 1,1-dioxide (CAS 150018-65-8)
- (S)-Tetrahydropyrrolo[1,2-b][1,2,5]thiadiazol-3(2H)-one 1,1-dioxide (CAS 176673-08-8)
- (S)-Tetrahydropyrrolo[1,2-a]pyrazine-1,4,6(7H)-trione (CAS 16364-60-6)
- Tetrahydropyrrolo[1,2-a]pyrazine-1,4,6(7H)-trione (CAS 18217-32-8)
- 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid (CAS 1214086-91-5)
- 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid (CAS 1782902-92-4)
- 1,3,4,6-Tetrahydropyrrolo[3,2-e]-[1,4]diazepine-2,5-dione (CAS 1099597-10-0)
- 4-Oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid (CAS 1369766-03-9)
Recommended Standards
- 1,2,3,4-Tetrahydrocyclopenta[b]indol-6-amine (CAS 933756-43-5)
- 1,3,4,5-Tetrahydrobenzo[cd]indol-4-amine (CAS 77963-70-3)
- 1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4(13),5,7-tetraene (CAS 27158-93-6)
- 1,3-Dimethylisoquinolin-5-amine (CAS 581813-08-3)
- (6,8-Dimethyl-9H-1,3,4,9-tetraaza-fluoren-2-yl-sulfanyl)-acetic acid (CAS 482616-05-7)
- 2-(8-Methyl-8-azabicyclo[3.2.1]Octan-3-ylidene)acetic acid (CAS 5811-04-1)
- Methyl 2-oxocyclodecane-1-carboxylate (CAS 76185-11-0)
- Dimethyl 3,5-piperidinedicarboxylate hydrochloride (CAS 1211510-61-0)
- Pirimicarb D6 (dimethylcarbamate D6) (CAS 1015854-66-6)
- 5-tert-butylpyrazine-2-sulfonyl chloride (CAS 2169587-53-3)
- N-(5-Amino-2-fluorophenyl)-2-isobutoxybenzamide (CAS 1020057-28-6)
- 3,5-Dichloro-N-(3-cyano-4-(phenylthio)phenyl)benzamide (CAS 306980-37-0)
- Prilocaine Impurity 44 (CAS CATO-C4X-193444)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
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