8-Methyl-8-azabicyclo[3.2.1]octan-3-yl isobutyrate CAS 495-80-7
| CAS No. | 495-80-7 |
| Molecular Formula | C12H21NO2 |
| Molecular Weight | 211.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl isobutyrate (CAS 495-80-7), molecular formula C12H21NO2 and molecular weight 211.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Methyl-8-azabicyclo[3.2.1]octan-3-yl isobutyrate (C12H21NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H21NO2 |
| Molecular Weight | 211.30 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 9-Propyl-9-azabicyclo[3.3.1]nonane-3-carboxylic acid (CAS 1208959-51-6)
- 3-Oxo-2-azabicyclo[2.2.1]heptan-2-carboxylic acid tert-butyl ester (CAS 167081-32-5)
- n-(2-(8-Azabicyclo[3.2.1]octan-3-yl)ethyl)-N-methylpropan-2-amine (CAS 1513209-78-3)
- 2-(8-Azabicyclo[3.2.1]octan-3-yl)-N,N-diethylethan-1-amine (CAS 1517319-34-4)
- n-(2-(8-Azabicyclo[3.2.1]octan-3-yl)ethyl)-N-methylpropan-1-amine (CAS 1538440-36-6)
- (2S)-2-({2-azabicyclo[2.2.1]heptan-2-yl}carbonylamino)propanoic acid (CAS 1485623-74-2)
- [6-(3-azabicyclo[3.1.0]hexan-3-yl)-2-methyl-3-pyridyl]methanol (CAS 1862126-05-3)
- 7-Benzyl-7-azabicyclo[2.2.1]heptane-1-carbonitrile (CAS 1087789-01-2)
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- Aceclidine Impurity 7 (CAS 211738-62-4)
- 6-Oxabicyclo[3.2.1]octane-2-carbaldehyde (CAS 2137650-35-0)
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- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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