2-((3-Cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide CAS 496018-60-1
| CAS No. | 496018-60-1 |
| Molecular Formula | C18H17FN4OS |
| Molecular Weight | 356.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((3-Cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((3-Cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 496018-60-1) is a high-purity analytical reference standard with the molecular formula C18H17FN4OS and a molecular weight of 356.42 g/mol.
2-((3-Cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide (C18H17FN4OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17FN4OS |
| Molecular Weight | 356.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- N-(3-Cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-3,4-dimethoxybenzamide (CAS 380903-56-0)
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- 2-((3-Cyano-4,6-dimethylpyridin-2-yl)thio)-N-(4-methyl-3-nitrophenyl)acetamide (CAS 332161-14-5)
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- [3-cyano-6-(isopropylamino)pyrazolo[1,5-a]pyridin-4-yl] trifluoromethanesulfonate (CAS 2649420-25-5)
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Recommended Standards
- 1-Phenyl-4-{7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}piperazine (CAS 338403-70-6)
- 2-((4-Methoxyphenyl)carbamoyl)thiophen-3-yl dimethylsulfamate (CAS 338794-69-7)
- 1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 393845-64-2)
- 2-((Bis(pyridin-2-ylmethyl)amino)methyl)quinolin-8-ol (CAS 648896-31-5)
- Methoxalic Anhydride (CAS 5781-55-5)
- 4,6-Dichloro-2-methylnicotinic Acid (CAS 693286-31-6)
- 5-Cyclopropoxy-2-methoxy-4-methylpyridine (CAS 1243388-52-4)
- 4-Ethyl-5-isopropyl-4h-1,2,4-triazole-3-thiol (CAS 66921-11-7)
- 2,3-Dimethoxy-6,7-dimethylnaphthalene (CAS 4676-58-8)
- (S)-1-(6-(trifluoromethyl)pyridin-3-yl)ethan-1-amine (CAS 1071435-62-5)
- BTP26C11-2CHO (CAS 2304444-53-7)
- 2-Phenyl-3H-indol-3-imine (CAS 6339-33-9)
- 1-Isothiocyanatoisoquinoline (CAS 1092516-12-5)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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