3-Amino-N-(2,5-dimethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide CAS 496019-15-9
| CAS No. | 496019-15-9 |
| Molecular Formula | C21H18N4O3S |
| Molecular Weight | 406.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-N-(2,5-dimethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-N-(2,5-dimethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-15-9), molecular formula C21H18N4O3S and molecular weight 406.46 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 3-Amino-N-(2,5-dimethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 406.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18N4O3S |
| Molecular Weight | 406.46 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-(2-(5-Amino-4-(4-methoxyphenyl)-1H-pyrazol-1-yl)-4-phenylthiazol-5-yl)acetic acid (CAS 956361-16-3)
- 3-Amino-N-(3,4-dimethoxyphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-31-9)
- N-(5-amino-2-fluorophenyl)-N-(phenylsulfonyl)benzenesulfonamide (CAS 1111507-12-0)
- 4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid (CAS 936890-98-1)
- 3-Amino-N-(2-(ethylthio)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-57-2)
- 2-Amino-5-oxo-4-(3,4,5-trimethoxyphenyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (CAS 293329-72-3)
- Benzyl 2-amino-6-(hydroxymethyl)-8-oxo-4-(pyridin-3-yl)-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 902313-04-6)
- (3-Amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(benzo[d][1,3]dioxol-5-yl)methanone (CAS 625377-80-2)
Recommended Standards
- 3,3',3''-(Methylsilanetriyl)tribenzoic acid (CAS 31825-53-3)
- 4,4',4''-(Methylsilanetriyl)tribenzoic acid (CAS 31825-52-2)
- (E)-4-Phenyl-1-(triphenylphosphoranylidene)but-3-en-2-one (CAS 98749-52-1)
- 4,5-Dibromo-2-(2-(4-chlorophenyl)-2-oxoethyl)pyridazin-3(2H)-one (CAS 303987-66-8)
- 1-(3-Amino-1h-1,2,4-triazol-1-yl)propan-2-ol (CAS 209793-30-6)
- 6-(Aminomethyl)-3-(difluoromethyl)-2-fluoropyridin-4-amine (CAS 1805117-04-7)
- JZL 184 (CAS 1101854-58-3)
- 1-(tert-Butylamino)-3-{2-[(3-methoxy-1,2,4-oxadiazol-5-yl)methoxy]phenoxy}-2-propanol hydrochloride (CAS 158446-41-4)
- 2-(Methylthio)spiro[3.3]heptane-2-carboxylic acid (CAS 1485191-94-3)
- Rel-(3R,4S)-4-aminotetrahydrothiophen-3-ol (CAS 53970-86-8)
- 3-Methyl-1-(pyridin-2-yl)-1h-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 1041205-19-9)
- 4-Oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidine-2-carboxylic acid (CAS 1779122-70-1)
- Methyl 5-ethylfuran-2-carboxylate (CAS 71387-70-7)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com