5-((3-Methylbenzyl)thio)-1H-1,2,4-triazol-3-amine CAS 496033-62-6
| CAS No. | 496033-62-6 |
| Molecular Formula | C10H12N4S |
| Molecular Weight | 220.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-((3-Methylbenzyl)thio)-1H-1,2,4-triazol-3-amine (CAS 496033-62-6) is a high-purity analytical reference standard with the molecular formula C10H12N4S and a molecular weight of 220.29 g/mol.
The molecular framework of 5-((3-Methylbenzyl)thio)-1H-1,2,4-triazol-3-amine (C10H12N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-((3-Methylbenzyl)thio)-1H-1,2,4-triazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N4S |
| Molecular Weight | 220.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylbenzyl Standards
- 5-((2-Methylbenzyl)thio)-1,2-dihydro-3h-1,2,4-triazol-3-imine (CAS 849524-40-9)
- 4-((4-Methylbenzyl)amino)-4-oxobutanoic acid (CAS 118290-70-3)
- Ethyl 2-((4-methylbenzyl)amino)-2-oxoacetate (CAS 349119-66-0)
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- (1-(2-Methylbenzyl)piperidin-2-yl)methanol (CAS 415701-94-9)
- (1-(2-Methylbenzyl)piperidin-3-yl)methanol (CAS 415716-13-1)
Recommended Standards
- 5-((p-Tolylthio)methyl)-2,4-dihydro-3H-pyrazol-3-one (CAS 371218-02-9)
- 5-(((4-Methoxyphenyl)thio)methyl)-1H-imidazole (CAS 40224-94-0)
- 5-(2,6-Dimethylpyrimidin-4-yl)-4-methylthiazol-2-amine (CAS 790706-79-5)
- 4-Propyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 90871-44-6)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-2-yl)propanoic acid (CAS 1260601-60-2)
- 3-(3-Fluorophenoxy)-2,2-dimethylpropanoic acid (CAS 1267001-89-7)
- 1-(2-Methylphenyl)cyclohexan-1-amine (CAS 118560-04-6)
- 1-(2,4-Difluorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-79-6)
- (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)vinyl)-1H-1,2,4-triazole (CAS 117857-45-1)
- tert-Butyl 6-(methylamino)-2-azaspiro[3.4]octane-2-carboxylate (CAS 2770982-13-1)
- 3-(2-chloroacetamido)-4-methyl-N-phenylbenzamide (CAS 1803609-27-9)
- Pyrrolo[1,2-a]thieno[2,3-e]pyrazin-6-amine (CAS 106723-67-5)
- 5217-47-0 BXB40M6A7W 1,3-Diethyl-2-thiobarbituric acid Barbituric acid, 1,3-diethyl-2-thio- (8CI) 1,3-Diethyldihydro-2-thioxopyrimidine-4,6(1H,5H)-dione 4,6(1H,5H)-Pyrimidinedione, 1,3-diethyldihydro-2-thioxo- N,N'-Diethylthiobarbituric acid N,N'-Diethyl-2-thiobarbituric acid 1,3-Diethylthiobarbituric acid EINECS 226-010-7 NSC 158284 UNII-BXB40M6A7W (CAS 5217-47-0)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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