3-(Methylsulfonyl)-1H-pyrazole CAS 49651-55-0
| CAS No. | 49651-55-0 |
| Molecular Formula | C4H6N2O2S |
| Molecular Weight | 146.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(Methylsulfonyl)-1H-pyrazole (CAS 49651-55-0), molecular formula C4H6N2O2S and molecular weight 146.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, 3-(Methylsulfonyl)-1H-pyrazole is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6N2O2S |
| Molecular Weight | 146.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylsulfonyl Standards
- 4-(Methylsulfonyl)-1H-pyrazole (CAS 1559062-17-7)
- 1-(Methylsulfonyl)-1H-pyrazole (CAS 262859-70-1)
- 2-(Methylsulfonyl)imidazole (CAS 27098-98-2)
- 3-methyl-3-methylsulfonyl-but-1-yne (CAS 2109226-54-0)
- 3-(Methylsulfonyl)-1H-pyrrole (CAS 82511-59-9)
- 5-methylsulfonyl-1H-1,2,4-triazole (CAS 3589-05-7)
- 2-Methyl-2-(methylsulfonyl)propanenitrile (CAS 14668-29-2)
- 1-(Methylsulfonyl)-3-pyrroline (CAS 246540-50-1)
Recommended Standards
- 2-Thioxoimidazolidine-4-carboxylic acid (CAS 32348-31-5)
- 3,4-Dimethoxy-1,2,5-thiadiazole (CAS 55904-37-5)
- 2-Amino-2,5-dihydrothiazole-4-carboxylic acid (CAS 606488-66-8)
- 3,4-Dimethyl-1,2,5-thiadiazole 1,1-dioxide (CAS 3775-12-0)
- Methyl 2,6-dichloro-3-hydroxybenzoate (CAS 142601-42-1)
- 2-(chloromethyl)-5-(4-chlorophenyl)-4-methyl-1,3-oxazole (CAS 70886-70-3)
- Ethyl quinazoline-8-carboxylate (CAS 1823945-25-0)
- 7-Bromo-5-chlorobenzofuran-3-carboxylic acid (CAS 1489133-32-5)
- n-(2-Fluorophenethyl)pentan-3-amine (CAS 1019480-18-2)
- 2-(p-Tolyl)furan (CAS 17113-32-5)
- n-(2-(Methylamino)ethyl)-2-nitrobenzenesulfonamide (CAS 1465047-64-6)
- 2-Propyl Valeraldehyde (CAS 18295-59-5)
- N'-(4-chlorobenzoyl)-2-(1H-pyrrol-1-yl)benzohydrazide (CAS 478063-00-2)
- Neuropeptide Y, porcine (CAS 82785-45-3)
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