4-chloro-2-fluoro-1,3-thiazole CAS 496791-62-9
| CAS No. | 496791-62-9 |
| Molecular Formula | C3HClFNS |
| Molecular Weight | 137.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-chloro-2-fluoro-1,3-thiazole (CAS 496791-62-9), a certified reference material (molecular formula C3HClFNS, MW 137.56 g/mol) for analytical method development and quality control.
The molecular framework of 4-chloro-2-fluoro-1,3-thiazole (C3HClFNS) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-chloro-2-fluoro-1,3-thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3HClFNS |
| Molecular Weight | 137.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-Amino-2-chlorobutanoic acid (CAS 4219-23-2)
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- 2-Chloroethyl methylcarbamate (CAS 22074-92-6)
- 4-Fluoro-3-(1H-tetrazol-1-yl)aniline (CAS 924871-65-8)
- 2-Formyl-4-methylthiophene-3-carboxylic acid (CAS 2167543-72-6)
- ((1R,5S)-3-oxabicyclo[3.1.0]Hexan-1-yl)methanamine (CAS 2306247-34-5)
- tert-Butyl N-(3-aminobutan-2-yl)carbamate (CAS 1334494-06-2)
- 4,7-Dihydroxy-1H-indole-3-carbonyl chloride (CAS 78942-72-0)
- 4-{1-[2-(7-chloroquinolin-4-yl)hydrazin-1-ylidene]ethyl}-1,3-thiazol-2-amine (CAS 1119219-51-0)
- 2-(3,3-Dimethyl-2-oxobutyl)isoindoline-1,3-dione (CAS 56658-35-6)
- (Z)-4-(4-Oxo-5-(pyridin-3-ylmethylene)-2-thioxothiazolidin-3-yl)benzoic acid (CAS 1427537-93-6)
- 2-imino-3,6-dimethyl-pyrazin-1-amine;2,4,6-trimethylbenzenesulfonic acid (CAS 1351515-90-6)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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