2-bromo-4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine CAS 496955-66-9
| CAS No. | 496955-66-9 |
| Molecular Formula | C7H5BrClN3 |
| Molecular Weight | 246.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-bromo-4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine.
CATO supplies 2-bromo-4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine (CAS 496955-66-9), a certified reference material (molecular formula C7H5BrClN3, MW 246.49 g/mol) for analytical method development and quality control.
Structurally, 2-bromo-4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine (C7H5BrClN3) contains a nitrile group, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 246.49 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-bromo-4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrClN3 |
| Molecular Weight | 246.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related bromo Standards
- 3-bromo-6-chloro-1H-indazol-5-amine (CAS 1000342-44-8)
- 3-Bromo-6-chloro-7-methylimidazo[1,2-b]pyridazine (CAS 1025066-16-3)
- 7-Bromo-4-chloro-2-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 1055057-39-0)
- 5-Bromo-2-(chloromethyl)benzo[d]oxazole (CAS 110704-48-8)
- 5-Bromo-6-chloro-2,3-dihydro-1H-indol-2-one (CAS 1153885-37-0)
- 8-Bromo-6-chloro-2-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1159813-15-6)
- 5-Bromo-4-chloro-3-hydroxyindole, 97% (CAS 117887-41-9)
- 6-Bromo-2-(chloromethyl)furo[3,2-b]pyridine (CAS 1186310-94-0)
Recommended Standards
- 2-(Bromomethyl)-7-chlorobenzo[d]oxazole (CAS 920036-25-5)
- 2-bromo-7-chloro-5-methyl-5H-pyrrolo[2,3-b]pyrazine (CAS 2089320-62-5)
- 2-(Bromomethyl)-5-chlorobenzo[d]oxazole (CAS 79784-31-9)
- 3-bromo-4-chloro-2-methyl-2H-pyrazolo[3,4-b]pyridine (CAS 2227574-30-1)
- n-Benzyl-4-methoxybenzene-1-sulfonamide (CAS 119059-70-0)
- 6-(Trifluoromethoxy)nicotinaldehyde (CAS 1361849-85-5)
- Sodium (S)-2-hydroxybutanoate (CAS 1629168-61-1)
- 1-(piperidin-3-yl)-1H-pyrazole-4-carboxylic acid hydrochloride (CAS 1461706-96-6)
- 5-Phenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine (CAS 405224-27-3)
- n-{[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]methyl}benzamide hydrobromide (CAS 1170893-47-6)
- 6-(4-Chlorophenyl)-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338751-64-7)
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- Nintedanib Impurity 85 (CAS CATO-C4X-181485)
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