N-(4-Amino-1,2,5-oxadiazol-3-yl)-2-bromoacetamide CAS 497224-40-5
| CAS No. | 497224-40-5 |
| Molecular Formula | C4H5BrN4O2 |
| Molecular Weight | 221.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(4-Amino-1,2,5-oxadiazol-3-yl)-2-bromoacetamide (CAS 497224-40-5), a certified reference material (molecular formula C4H5BrN4O2, MW 221.01 g/mol) for analytical method development and quality control.
N-(4-Amino-1,2,5-oxadiazol-3-yl)-2-bromoacetamide (C4H5BrN4O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), N-(4-Amino-1,2,5-oxadiazol-3-yl)-2-bromoacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H5BrN4O2 |
| Molecular Weight | 221.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 2-Amino-5-iodopyrimidine (CAS 1445-39-2)
- 2-Amino-4-iodopyrimidine (CAS 815610-16-3)
- 3-Amino-5-bromo-6-fluoro-1-methylpyridin-2(1H)-one (CAS 2795135-40-7)
- Methyl 2-amino-4,6-dichloronicotinate (CAS 1044872-40-3)
- 2-Amino-3,5-dichloro-N-hydroxybenzamide (CAS 1130-71-8)
- Methyl 2-amino-3,5-dichloroisonicotinate (CAS 1227002-69-8)
- Methyl 3-amino-4,6-dichloropicolinate (CAS 1379329-39-1)
- Methyl 6-amino-3,5-dichloropicolinate (CAS 1416374-91-8)
Recommended Standards
- 4-FLUOROISOPHTHALOYL DICHLORIDE (CAS 327-94-6)
- Phosphoramide mustard (CAS 10159-53-2)
- 4-(2-Bromoacetyl)-3-hydroxyfuran-2(5H)-one (CAS 99983-31-0)
- 3-Bromo-6-fluoro-2-methoxyphenol (CAS 1026796-50-8)
- 3-benzamidopyridine-4-carboxylic acid (CAS 1461601-05-7)
- tert-Butyl 2,7-diazaspiro[4.4]nonane-2-carboxylate hydrochloride (CAS 1147423-20-8)
- Methyl 5-[(4-chlorophenyl)sulfanyl]-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate (CAS 449778-53-4)
- 2-Hydroxy-3-(methoxycarbonyl)benzoic acid (CAS 101670-85-3)
- BCN-exo-PEG3-NH2 (CAS 1841134-72-2)
- Roxadustat Impurity 142 (CAS CATO-C4X-2213142)
- Dolutegravir Impurity 55 (CAS CATO-C4X-162055)
- 5-(Chloromethyl)-3-(1-(4-fluorophenyl)cyclopropyl)-1,2,4-oxadiazole (CAS 1021436-47-4)
- 2-(2-Methyl-1H-indol-3-yl)ethanamine (CAS 2731-06-8)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com