4-Phenyl-2-piperazinecarboxylic acid monohydrochloride CAS 49746-45-4
| CAS No. | 49746-45-4 |
| Molecular Formula | C11H14N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Phenyl-2-piperazinecarboxylic acid monohydrochloride (CAS 49746-45-4), molecular formula C11H14N2O2HCl and molecular weight 242.70 g/mol, is a CATO reference standard with documented purity and traceability.
4-Phenyl-2-piperazinecarboxylic acid monohydrochloride (C11H14N2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 4-Phenyl-2-piperazinecarboxylic acid monohydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H14N2O2 HCl |
| Molecular Weight | 242.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 1-(3,5-Dichlorophenyl)-2-(isopropylamino)ethan-1-ol (CAS 78982-75-9)
- 2,2-dimethoxy-1-(piperazin-1-yl)ethan-1-one (CAS 1955554-66-1)
- 1-(1H-Benzo[d]imidazol-5-yl)-N-methylmethanamine (CAS 886851-32-7)
- tert-Butyl (2-oxopiperidin-1-yl)carbamate (CAS 1123192-34-6)
- N-(Furan-2-ylmethyl)-6-methoxypyridazine-3-carboxamide (CAS 1251671-02-9)
- 6-Chloro-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-ol (CAS 1805992-43-1)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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