3-Amino-N-cyclopropyl-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide CAS 499118-04-6
| CAS No. | 499118-04-6 |
| Molecular Formula | C19H16F3N3OS |
| Molecular Weight | 391.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 391.41 g/mol gives 3-Amino-N-cyclopropyl-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Amino-N-cyclopropyl-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 499118-04-6), a certified reference material (molecular formula C19H16F3N3OS, MW 391.41 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 3-Amino-N-cyclopropyl-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 391.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-N-cyclopropyl-6-(p-tolyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F3N3OS |
| Molecular Weight | 391.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-((6-Benzyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide (CAS 723748-29-6)
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- 2-((3-Cyano-6-(p-tolyl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide (CAS 488809-84-3)
- Ethyl 6-methyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}-3-quinolinecarboxylate (CAS 477847-15-7)
- 2-Chloro-6-ethylpyrazine (CAS 1209458-23-0)
- N-(tert-Butyl)-2-(3-(4-fluorophenyl)-2-oxoimidazolidin-1-yl)acetamide (CAS 1286697-16-2)
- 2-Allyl-6-nitro-1,2,3,4-tetrahydroisoquinoline (CAS 207804-95-3)
- 5-Amino-2-(trifluoromethoxy)benzonitrile (CAS 1261523-71-0)
- (2s)-3-Aminopropane-1,2-diol hydrochloride (CAS 209849-99-0)
- Ethyl 5-morpholino-3-phenyl-1,2,4-triazine-6-carboxylate (CAS 866049-07-2)
- Methyl 5-nitro-2-vinylbenzoate (CAS 439937-53-8)
- 3-Bromo-4-phenoxyaniline, 97% (CAS 1159607-48-3)
- Ethyl N-(tert-butoxycarbonyl)-N-(cyanomethyl)glycinate (CAS 339182-12-6)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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