4-Ethoxymethylene-2-(3-trifluoromethyl-phenyl)-4H-isoquinoline-1,3-dione CAS 499229-40-2
| CAS No. | 499229-40-2 |
| Molecular Formula | C19H14F3NO3 |
| Molecular Weight | 361.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Ethoxymethylene-2-(3-trifluoromethyl-phenyl)-4H-isoquinoline-1,3-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Ethoxymethylene-2-(3-trifluoromethyl-phenyl)-4H-isoquinoline-1,3-dione (CAS 499229-40-2), molecular formula C19H14F3NO3 and molecular weight 361.31 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Ethoxymethylene-2-(3-trifluoromethyl-phenyl)-4H-isoquinoline-1,3-dione (C19H14F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 361.31 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Ethoxymethylene-2-(3-trifluoromethyl-phenyl)-4H-isoquinoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14F3NO3 |
| Molecular Weight | 361.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethoxymethylene Standards
- 4-(4-Ethoxymethylene-1,3-dioxo-3,4-dihydro-1H-isoquinolin-2-yl)-benzoic acid ethyl ester (CAS 750607-46-6)
- 4-Ethoxymethylene-2-(4-ethoxy-phenyl)-4H-isoquinoline-1,3-dione (CAS 750607-40-0)
- 4-Ethoxymethylene-2-(4-isopropyl-phenyl)-4H-isoquinoline-1,3-dione (CAS 565168-52-7)
- (Ethoxymethylene)triphenylphosphorane (CAS 55812-81-2)
- 2-Benzyl-4-ethoxymethylene-4H-isoquinoline-1,3-dione (CAS 749219-34-9)
- 3-(4-(Ethoxymethylene)-1,3-dioxo-3,4-dihydroisoquinolin-2(1h)-yl)-n,n-diethylbenzenesulfonamide (CAS 565195-44-0)
- (E)-5-(Ethoxymethylene)-3-phenethyl-2-thioxothiazolidin-4-one (CAS 828299-72-5)
- 4-(Ethoxymethylene)-2-(naphthalen-1-yl)oxazol-5(4H)-one (CAS 269733-57-5)
Recommended Standards
- 4,5-Dimethyl 1-{2-oxo-2-[(phenylcarbamoyl)amino]ethyl}-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 892277-85-9)
- N-(2-Methoxyphenyl)-5-(2-(trifluoromethyl)phenyl)furan-2-carboxamide (CAS 622805-19-0)
- 1-Acetyl-3-(4-(trifluoromethyl)phenyl)indolizin-2-yl acetate (CAS 477870-94-3)
- N-Nitroso Nicardipine USP Related Compound A (CAS CATO-C4X-171020)
- 1-(3-Bromo-5-methylthiophen-2-yl)ethan-1-amine (CAS 1532059-90-7)
- 4-Methyl-5,6,7,8-tetrahydroquinazolin-2-ol (CAS 88267-97-4)
- (Nitrosobenzene-N,O)bis(triphenylphosphine)platinum (CAS 57718-95-3)
- 5-iodo-2-(1H-tetrazol-1-yl)benzoic acid (CAS 749920-55-6)
- 2,4-Dimethyl-2,3-dihydrobenzofuran-5-amine (CAS 153782-58-2)
- Ethyl 3-(4-chloro-5-methyl-1h-pyrazol-1-yl)-2-(methylamino)propanoate (CAS 1340558-65-7)
- 2-Methylpyrazolo[1,5-a]pyrimidine-6-carbothioamide (CAS 1193389-99-9)
- 2-(4-Bromophenyl)-2-azaspiro[4.4]Nonane-1,3-dione (CAS 61343-15-5)
- (r)-3-Fluoro-n-(piperidin-3-yl)benzamide hydrochloride (CAS 1286207-73-5)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
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