2-Amino-5-(4-chlorobenzyl)-6-methylpyrimidin-4(3H)-one CAS 500157-65-3
| CAS No. | 500157-65-3 |
| Molecular Formula | C12H12ClN3O |
| Molecular Weight | 249.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Amino-5-(4-chlorobenzyl)-6-methylpyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Amino-5-(4-chlorobenzyl)-6-methylpyrimidin-4(3H)-one (CAS 500157-65-3) is a high-purity analytical reference standard with the molecular formula C12H12ClN3O and a molecular weight of 249.70 g/mol.
Based on its molecular formula C12H12ClN3O, 2-Amino-5-(4-chlorobenzyl)-6-methylpyrimidin-4(3H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 249.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3O |
| Molecular Weight | 249.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 6-Amino-3-chloro-6,7,8,9-tetrahydro-11h-pyrido[2,1-b]quinazolin-11-one (CAS 1375473-60-1)
- ((5-Amino-2-chloro-4-fluorophenyl)thio)methyl acetate (CAS 131533-07-8)
- (5-Amino-2-(4-chlorophenoxy)phenyl)methanol (CAS 924869-26-1)
- 4-Amino-5-chloro-N-ethyl-N-methylpyridine-3-sulfonamide (CAS 1352521-38-0)
- (2-Amino-5-chloro-4-fluorophenyl)(phenyl)methanone (CAS 1433904-07-4)
- (2-Amino-4-chlorophenyl)(2-fluorophenyl)methanone (CAS 203303-05-3)
- (2-Amino-5-chlorophenyl)(4-fluorophenyl)methanone (CAS 784-40-7)
- 2-Amino-5-(aminosulfonyl)-4-chlorobenzamide (CAS 34121-17-0)
Recommended Standards
- 2-{[(4-chlorophenyl)methyl]amino}-6-methyl-3,4-dihydropyrimidin-4-one (CAS 714214-12-7)
- 2-Chloro-3-(morpholin-4-yl)quinoxaline (CAS 6641-44-7)
- 2-(6-Chloropyridin-3-yl)-1,3-diazaspiro[4.4]Non-1-en-4-one (CAS 2306264-58-2)
- 2-Chloro-4-morpholinoquinazoline (CAS 39213-05-3)
- tert-Butyl 4-[(5-nitropyridin-2-yl)oxy]piperidine-1-carboxylate (CAS 346665-40-5)
- MEthyl 4-[(cyclopropylsulfamoyl)methyl]benzoate (CAS 1091876-96-8)
- 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanehydrazide hydrochloride (CAS 293298-33-6)
- Mal-amido-PEG2-C2-acid (CAS 756525-98-1)
- 1-(3-Hydroxy-3-methylbut-1-yn-1-yl)anthracene-9,10-dione (CAS 112878-62-3)
- 1-Fluoro-2-(fluoromethyl)-4-nitrobenzene (CAS 63878-68-2)
- 2-Amino-6-(naphthalen-2-ylsulfonyl)quinazolin-4(1H)-one (CAS 52979-11-0)
- 4-Hydroxy-3-methylbutanenitrile (CAS 64404-55-3)
- Methyl 2-acetamidobenzoate (CAS 2719-08-6)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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