Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-4-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate CAS 500188-21-6
| CAS No. | 500188-21-6 |
| Molecular Formula | C23H17F3N2O6S |
| Molecular Weight | 506.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 506.45 g/mol gives Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-4-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-4-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate (CAS 500188-21-6) is a high-purity analytical reference standard with the molecular formula C23H17F3N2O6S and a molecular weight of 506.45 g/mol.
Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-4-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate (C23H17F3N2O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-4-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17F3N2O6S |
| Molecular Weight | 506.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (2S,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,5,6-pentaol (CAS 61473-64-1)
- Maltotriitol (CAS 32860-62-1)
- 4-((2,3-Dichlorophenyl)thio)-1-(4-methoxyphenyl)-2-phenyl-6,7-dihydro-1H-indole-5-carbaldehyde (CAS 477869-32-2)
- Fmoc-Dab(Dnp)-OH (CAS 1263047-22-8)
- N2-(3-chloro-2-methylphenyl)-6-(chloromethyl)-1,3,5-triazine-2,4-diamine (CAS 644959-92-2)
- NeurotransRed C2M, 90% (CAS 872979-87-8)
- [(2,4-dimethoxyphenyl)methyl]hydrazine hydrochloride (CAS 462059-71-8)
- (S)-1-(5-chloro-2-fluorophenyl)-2-methoxyethan-1-amine (CAS 1270076-06-6)
- (r)-n-((r)-1-(Indolin-4-yl)ethyl)-2-methylpropane-2-sulfinamide (CAS 2647886-95-9)
- Lansoprazole Impurity 11 (CAS 1329838-16-5)
- 3-(1-(Tert-butoxycarbonyl)azetidin-3-yl)cyclobutane-1-carboxylic acid (CAS 1989659-47-3)
- 4-(2-(Methylthio)ethyl)pyridine (CAS 124528-30-9)
- N-[4-(2-Ethoxyethoxy)benzyl]-3-(2-methoxyethoxy)aniline (CAS 1040686-61-0)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
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