6-Bromo-2-(trifluoromethyl)quinolin-4(1H)-one CAS 500562-58-3
| CAS No. | 500562-58-3 |
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 500562-58-3), molecular formula C10H5BrF3NO and molecular weight 292.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromo-2-(trifluoromethyl)quinolin-4(1H)-one (C10H5BrF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 6-Bromo-2-(trifluoromethyl)quinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-6-(trifluoromethoxy)quinoline (CAS 1020253-25-1)
- 3-Bromo-6-(trifluoromethoxy)quinoline (CAS 1059064-17-3)
- 5-Bromo-8-(trifluoromethoxy)quinoline (CAS 1065074-23-8)
- 5-Bromo-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-40-1)
- 8-Bromo-5-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-42-3)
- 8-Bromo-6-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-51-4)
- 6-Bromo-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-55-8)
- 8-Bromo-5-(trifluoromethoxy)quinoline (CAS 1133115-91-9)
Recommended Standards
- 5-Bromo-3-(trifluoroacetyl)indole (CAS 32387-18-1)
- 6-Bromo-2-hydroxy-4-(trifluoromethyl)quinoline (CAS 328955-61-9)
- 5-(4-Bromo-2-(trifluoromethyl)phenyl)oxazole (CAS 2029361-43-9)
- 7-Bromo-4-(trifluoromethyl)quinolin-2-ol (CAS 847900-73-6)
- 3-Methylpyridine-2-carbohydrazide (CAS 958453-96-8)
- N-(4-bromobenzyl)-N-butylbutan-1-amine (CAS 433228-38-7)
- 2-(1H-Pyrrol-3-yl)ethanamine Hydrochloride (CAS 6662-17-5)
- 1-[5-(N-methoxy-C-methylcarbonimidoyl)thiophen-2-yl]ethanone (CAS 114774-08-2)
- Cilostazol USP Related Compound A (CAS 54197-66-9)
- 4,5-Dimethyl-1,3-oxazol-2-amine hydrochloride (CAS 91114-85-1)
- Diethylcarbamazine Citrate (CAS 1642-54-2)
- Isoindolin-4-ylmethanol (CAS 127168-95-0)
- 1-(2-Fluorophenyl)cyclopropane-1-carbothioamide (CAS 1379028-70-2)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com