4-(((1,3,4-Thiadiazol-2-yl)sulfonyl)methyl)-N-(4-fluorophenyl)benzamide CAS 500568-12-7

Purity 97%+In StockPharmaceutical Standards
CAS No.500568-12-7
Molecular FormulaC16H12FN3O3S2
Molecular Weight377.41 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(((1,3,4-Thiadiazol-2-yl)sulfonyl)methyl)-N-(4-fluorophenyl)benzamide CAS 500568-12-7 chemical structure

Description

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(((1,3,4-Thiadiazol-2-yl)sulfonyl)methyl)-N-(4-fluorophenyl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

4-(((1,3,4-Thiadiazol-2-yl)sulfonyl)methyl)-N-(4-fluorophenyl)benzamide (CAS 500568-12-7), molecular formula C16H12FN3O3S2 and molecular weight 377.41 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H12FN3O3S2
Molecular Weight377.41 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms2

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