4-(Chloromethyl)-N-(3,4-difluorophenyl)benzamide CAS 500568-86-5

Description

Compared with other compounds in its class, the molecular weight of 281.69 g/mol gives 4-(Chloromethyl)-N-(3,4-difluorophenyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(Chloromethyl)-N-(3,4-difluorophenyl)benzamide (CAS 500568-86-5), molecular formula C14H10ClF2NO and molecular weight 281.69 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(Chloromethyl)-N-(3,4-difluorophenyl)benzamide (C14H10ClF2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Chloromethyl)-N-(3,4-difluorophenyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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