2H-Pyrrolo[2,3-d][1,2,3]thiadiazole CAS 500722-43-0
| CAS No. | 500722-43-0 |
| Molecular Formula | C4H3N3S |
| Molecular Weight | 125.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2H-Pyrrolo[2,3-d][1,2,3]thiadiazole (C4H3N3S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2H-Pyrrolo[2,3-d][1,2,3]thiadiazole (CAS 500722-43-0), a certified reference material (molecular formula C4H3N3S, MW 125.15 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2H-Pyrrolo[2,3-d][1,2,3]thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3N3S |
| Molecular Weight | 125.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related H Standards
- 2H-Pyrrolo[3,2-d][1,2,3]thiadiazole (CAS 500722-42-9)
- 2H-Pyrrolo[3,4-d][1,2,3]thiadiazole (CAS 67409-30-7)
- 2H-Pyrrolo[2,3-d]thiazole (CAS 72332-79-7)
- 2H-Pyrrolo[3,4-d]thiazole (CAS 72332-80-0)
- 4H-Pyrrolo[2,3-d]thiazole (CAS 298699-45-3)
- 4H-Pyrrolo[3,2-d]thiazole (CAS 59839-75-7)
- pyrrolo[1,2-a]pyrazine (CAS 274-45-3)
- 271-29-4 1H-Pyrrolo(2,3-c)pyridine 5-23-06-00305 (Beilstein Handbook Reference) 6-Azaindole BRN 0109685 1,6-Diazaindene Harmyrine (CAS 271-29-4)
Recommended Standards
- 2-Aminothiazole-5-carbonitrile (CAS 51640-52-9)
- 2-Aminothiazole-4-carbonitrile (CAS 98027-21-5)
- 1H-Pyrazolo[4,3-d]thiazole (CAS 392-77-8)
- 2-Pyridinamine,5-methyl-,1-oxide (CAS 66362-95-6)
- 2-(Difluoromethyl)-3-nitro-6-(trifluoromethoxy)pyridine-5-carbonyl chloride (CAS 1804438-48-9)
- N-(3-Butyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)acetamide (CAS 32479-70-2)
- 6-Oxo-1,6-dihydropyridine-3-carbonitrile (CAS 95891-30-8)
- 6-Chlorocinnolin-3(2H)-one (CAS 101495-52-7)
- N-(3-amino-4-methoxyphenyl)methanesulfonamide hydrochloride (CAS 188630-76-4)
- 4-Chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)benzamide (CAS 303150-63-2)
- 2,2,2-Trifluoroethyl n-propylcarbamate (CAS 1221723-10-9)
- N-[(1E)-{[(2-chloro-4-fluorophenyl)methoxy]imino}methyl]-2-(3,3-dimethyl-2-oxoazetidin-1-yl)-3-phenylpropanamide (CAS 338748-55-3)
- 1-{4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl}propan-1-ol (CAS 937049-19-9)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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