8-Aza-7-deaza-2-deoxy-N2-DMF-5-O-DMT-guanosine 3-CE phosphoramidite CAS 500891-26-9
| CAS No. | 500891-26-9 |
| Molecular Formula | C43H53N8O7P |
| Molecular Weight | 824.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Aza-7-deaza-2-deoxy-N2-DMF-5-O-DMT-guanosine 3-CE phosphoramidite (CAS 500891-26-9), molecular formula C43H53N8O7P and molecular weight 824.90 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Aza-7-deaza-2-deoxy-N2-DMF-5-O-DMT-guanosine 3-CE phosphoramidite (C43H53N8O7P) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 8-Aza-7-deaza-2-deoxy-N2-DMF-5-O-DMT-guanosine 3-CE phosphoramidite meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C43H53N8O7P |
| Molecular Weight | 824.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 8 |
Related Aza Standards
- 8-Aza-7-deaza-2’-deoxy-N2-DMF-5’-O-DMT (CAS 869355-14-6)
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- 7-Deaza-2'-deoxy-7-iodoadenosine (CAS 166247-63-8)
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- 7-Deaza-2'-C-methylguanosine (CAS 443642-38-4)
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Recommended Standards
- (2R,3R,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 196391-62-5)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
- Apixaban Impurity 97 (CAS 1998079-14-3)
- Candesartan Cilexetil Impurity 17 (CAS 1798004-41-7)
- 1-(4-(((2-Aminoethyl)thio)methyl)thiazol-2-yl)guanidine (CAS 71916-66-0)
- 2-Chloro-5-(difluoromethoxy)-3-methylpyridine (CAS 1315360-83-8)
- 2-(3-Bromo-4-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1157138-03-8)
- 1,5-Dimethyl-3-(pyrrolidin-1-yl)-1H-pyrazol-4-amine dihydrochloride (CAS 1269052-78-9)
- 1-(4-Chlorobenzoyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 260789-24-0)
- 1-(Adamantan-1-yl)butan-2-amine (CAS 779989-20-7)
- 4-Chloro-2-((tetrahydro-2H-pyran-4-yl)oxy)aniline (CAS 1342210-13-2)
- 4-(2,3-Difluorophenyl)benzoic acid (CAS 505082-93-9)
- Methyl 2-oxo-2,3-dihydro-1H-pyrrolizine-6-carboxylate (CAS 2388474-73-3)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
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