4-Iodo-5-(p-tolyl)-1H-pyrazol-3-amine CAS 501026-63-7
| CAS No. | 501026-63-7 |
| Molecular Formula | C10H10IN3 |
| Molecular Weight | 299.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Iodo-5-(p-tolyl)-1H-pyrazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-Iodo-5-(p-tolyl)-1H-pyrazol-3-amine (CAS 501026-63-7), a certified reference material (molecular formula C10H10IN3, MW 299.11 g/mol) for analytical method development and quality control.
The molecular framework of 4-Iodo-5-(p-tolyl)-1H-pyrazol-3-amine (C10H10IN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H10IN3 |
| Molecular Weight | 299.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iodo Standards
- 7-Iodo-3-(1-methylcyclopropyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1057393-50-6)
- 3-Iodo-5,7-dimethylquinolin-4(1H)-one (CAS 1330750-83-8)
- 3-Iodo-7,8-dimethylquinolin-4(1H)-one (CAS 1330751-09-1)
- 3-Iodo-2,8-dimethylquinolin-4(1H)-one (CAS 1330754-02-3)
- 3-Iodo-6,8-dimethylquinolin-4(1H)-one (CAS 1330755-90-2)
- 5-Iodo-6-methoxy-2-methylquinoline (CAS 1346169-93-4)
- 6-Iodo-1,8-dimethylquinolin-2(1H)-one (CAS 135715-93-4)
- 5-Iodo-1,2-dimethyl-1H-indole-3-carbaldehyde (CAS 1416338-48-1)
Recommended Standards
- 4-Iodo-5-(o-tolyl)-1H-pyrazol-3-amine (CAS 501100-30-7)
- 5-(3-Iodophenyl)-5-oxopentanenitrile (CAS 898767-94-7)
- 4-Iodo-5-(m-tolyl)-1H-pyrazol-3-amine (CAS 501100-29-4)
- 5-(4-Iodophenyl)-5-oxovaleronitrile (CAS 898767-84-5)
- 6-Cyclohexyl-hexanoic acid (CAS 4354-56-7)
- (S)-2-((4-Ethyl-3-methylisoxazol-5-yl)amino)pentanamide (CAS 794565-19-8)
- Fenoprofen Calcium Dihydrate (CAS 53746-45-5)
- 4-Fluoroindoline-5-carbonitrile (CAS 2092093-82-6)
- 3-Amino-2-(1H-pyrazol-1-yl)cyclobutan-1-ol (CAS 1909336-44-2)
- [3-methyl-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1006444-38-7)
- 7-(Bromomethyl)benzo[d]thiazole (CAS 2089292-84-0)
- (S)-2-Amino-2-methylhex-5-enoic acid (CAS 1011309-60-6)
- 5-Methoxy-1H-indol-3-ol (CAS 909031-92-1)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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