Methyl 4-(3-chlorophenyl)-2,4-dioxobutanoate CAS 501653-40-3
| CAS No. | 501653-40-3 |
| Molecular Formula | C11H9ClO4 |
| Molecular Weight | 240.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-(3-chlorophenyl)-2,4-dioxobutanoate.
Methyl 4-(3-chlorophenyl)-2,4-dioxobutanoate (CAS 501653-40-3), molecular formula C11H9ClO4 and molecular weight 240.64 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Methyl 4-(3-chlorophenyl)-2,4-dioxobutanoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 240.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-(3-chlorophenyl)-2,4-dioxobutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9ClO4 |
| Molecular Weight | 240.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
Related Methyl Standards
- 2-(3-Chlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1399658-16-2)
- 2-(2-Chlorophenyl)-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1399658-55-9)
- 2-(4-Chlorophenyl)-5-oxotetrahydrofuran-2-carboxylic acid (CAS 34971-17-0)
- Methyl 4-(2-chlorophenyl)-2,4-dioxobutanoate (CAS 451485-68-0)
- Methyl 4-(4-chlorophenyl)-2,4-dioxobutanoate (CAS 39757-35-2)
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