Tert-butyl 4-(p-tolylamino)piperidine-1-carboxylate CAS 501673-99-0
| CAS No. | 501673-99-0 |
| Molecular Formula | C17H26N2O2 |
| Molecular Weight | 290.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tert-butyl 4-(p-tolylamino)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tert-butyl 4-(p-tolylamino)piperidine-1-carboxylate (CAS 501673-99-0) is a high-purity analytical reference standard with the molecular formula C17H26N2O2 and a molecular weight of 290.40 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Tert-butyl 4-(p-tolylamino)piperidine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 290.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H26N2O2 |
| Molecular Weight | 290.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl 4-(amino(phenyl)methyl)piperidine-1-carboxylate (CAS 612532-09-9)
- Tert-butyl 4-[(3-methylphenyl)amino]piperidine-1-carboxylate (CAS 679409-60-0)
- tert-Butyl 4-(4-aminobenzyl)piperidine-1-carboxylate (CAS 221532-96-3)
- tert-Butyl 4-[(4-methylphenyl)methyl]piperazine-1-carboxylate (CAS 779989-61-6)
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