1-(2-Fluorophenyl)-3-(6-methylpyridin-2-yl)urea CAS 501685-71-8
| CAS No. | 501685-71-8 |
| Molecular Formula | C13H12FN3O |
| Molecular Weight | 245.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Fluorophenyl)-3-(6-methylpyridin-2-yl)urea.
1-(2-Fluorophenyl)-3-(6-methylpyridin-2-yl)urea (CAS 501685-71-8), molecular formula C13H12FN3O and molecular weight 245.25 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2-Fluorophenyl)-3-(6-methylpyridin-2-yl)urea (C13H12FN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Fluorophenyl)-3-(6-methylpyridin-2-yl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12FN3O |
| Molecular Weight | 245.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)-3-(pyridin-2-yl)propanoic acid (CAS 1017136-64-9)
- 2-(4-Fluorophenyl)-3-(pyridin-3-yl)propanoic acid (CAS 1017352-33-8)
- 2-(2-fluorophenyl)-2-(phenylamino)acetic acid (CAS 1146747-23-0)
- 2-((4-Fluorophenyl)amino)-2-phenylacetic acid (CAS 124573-79-1)
- N-(4-fluorophenyl)-2-(4-hydroxyphenyl)acetamide (CAS 131179-72-1)
- 2-(4-Fluorophenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1355218-11-9)
- n-(2-Fluorophenyl)-4-methoxybenzamide (CAS 143925-52-4)
- Methyl 6-(2-fluorophenyl)-2-methylnicotinate (CAS 1447958-23-7)
Recommended Standards
- [(2Z)-2-(2-ethoxy-2-oxoethylidene)-4-oxo-1,3-thiazolidin-3-yl]acetic acid (CAS 730956-98-6)
- 1-(Ethanesulfonyl)-2-methoxy-4-nitrobenzene (CAS 75259-32-4)
- (S)-3-((5-amino-1,3,4-thiadiazol-2-yl)thio)-1,1,1-trifluoropropan-2-ol (CAS 477762-55-3)
- 1-(tert-Butoxycarbonyl)-4-fluoro-1,2,5,6-tetrahydropyridine-3-carboxylic acid (CAS 2301886-27-9)
- H-L-Phe-L-Phe-L-Phe-L-Leu-L-Lys-γ-Pip-OH (CAS CATO-CPTD788749)
- 4-(Difluoromethyl)-3-methylbenzonitrile (CAS 1261731-65-0)
- H-Phe-Ser-Trp-Phe-Val-Asp-Asp-Val-Glu-Val-Asn-Thr-Ala-Thr-Thr-Lys-Pro-Arg-OH (CAS CATO-CPTD788663)
- 2-(2-Bromo-4-nitrophenyl)propan-2-ol (CAS 1935889-83-0)
- 2,3,5-Tribromo-4-ethylthiophene (CAS 83663-35-8)
- N-(4,6-Dimethylpyrimidin-2-yl)-2-oxo-2H-chromene-6-sulfonamide (CAS 646513-24-8)
- 3-(4-(tert-Butyl)phenyl)-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 676152-78-6)
- Peptide Impurity 82 (CAS 10491-78-8)
- Permethrin Impurity 10 (CAS 63406-18-8)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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