3-(4-Chlorophenoxy)benzene-1-sulfonyl chloride CAS 501697-55-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Chlorophenoxy)benzene-1-sulfonyl chloride.

3-(4-Chlorophenoxy)benzene-1-sulfonyl chloride (CAS 501697-55-8) is a high-purity analytical reference standard with the molecular formula C12H8Cl2O3S and a molecular weight of 303.16 g/mol.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-(4-Chlorophenoxy)benzene-1-sulfonyl chloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 303.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-Chlorophenoxy)benzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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