4-(2,2-difluoroethoxy)-3,5-dimethoxybenzaldehyde CAS 501699-83-8
| CAS No. | 501699-83-8 |
| Molecular Formula | C11H12F2O4 |
| Molecular Weight | 246.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.21 g/mol gives 4-(2,2-difluoroethoxy)-3,5-dimethoxybenzaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(2,2-difluoroethoxy)-3,5-dimethoxybenzaldehyde (CAS 501699-83-8) is a high-purity analytical reference standard with the molecular formula C11H12F2O4 and a molecular weight of 246.21 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-(2,2-difluoroethoxy)-3,5-dimethoxybenzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2,2-difluoroethoxy)-3,5-dimethoxybenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12F2O4 |
| Molecular Weight | 246.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related difluoroethoxy Standards
- 4-(2,2-difluoroethoxy)-3-nitrobenzoic acid (CAS 1178286-57-1)
- (1e)-1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanone oxime (CAS 1216325-61-9)
- 3-(3-(2,2-Difluoroethoxy)-4-nitro-1H-pyrazol-1-yl)propan-1-amine (CAS 1855945-09-3)
- 2-(2,2-Difluoroethoxy)benzyl bromide (CAS 1179229-29-8)
- 4-(2,2-Difluoroethoxy)benzyl bromide (CAS 1184195-23-0)
- 2-(2,2-difluoroethoxy)-5-methanesulfonylaniline (CAS 1556789-81-1)
- 4-(2,2-Difluoroethoxy)-2-trifluoromethylphenylamine (CAS 1242458-44-1)
- 2-(2,2-Difluoroethoxy)-5-(trifluoromethyl)aniline (CAS 937597-00-7)
Recommended Standards
- 3,3’-Difluorobenzil (CAS 70028-89-6)
- 4-(Difluoromethoxy)-3-ethoxybenzohydrazide (CAS 832740-84-8)
- 3-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 826995-51-1)
- 4-(Furan-2-yl)-6-(trifluoromethyl)pyrimidine-2-thiol (CAS 329710-06-7)
- (4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid (CAS 875446-29-0)
- N-(4-Isopropylphenyl)cyclopropanesulfonamide (CAS 1207041-39-1)
- (E)-3-Bromo-2-((4-nitrobenzylidene)amino)-9H-fluoren-9-one (CAS 3405-15-0)
- Triclopyr-2-Butoxyethyl Ester (CAS 64700-56-7)
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- 6-Methoxy-3-phenylquinolin-2-amine (CAS 855837-36-4)
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- Vinyl magnesium bromide solution (CAS 1826-67-1)
- 4-Azaspiro[2.5]octane-7-carbonitrile (CAS 2089986-23-0)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
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