1,2-Diphenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione CAS 5021-54-5
| CAS No. | 5021-54-5 |
| Molecular Formula | C20H18N2S |
| Molecular Weight | 318.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,2-Diphenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (C20H18N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1,2-Diphenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (CAS 5021-54-5), a certified reference material (molecular formula C20H18N2S, MW 318.44 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,2-Diphenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18N2S |
| Molecular Weight | 318.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 2-Amino-3,5-dibromopyrazine (CAS 24241-18-7)
- Aconitic Acid (CAS 499-12-7)
- Iron-<SUP>57</SUP>Fe (CAS 14762-69-7)
- 5-Chloro-3H-quinazolin-4-one (CAS 60233-66-1)
- Manganese(III) oxide (CAS 1317-34-6)
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