4-Hydroxy-1H-pyrrol-2(5H)-one CAS 503-83-3
| CAS No. | 503-83-3 |
| Molecular Formula | C4H5NO2 |
| Molecular Weight | 99.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Hydroxy-1H-pyrrol-2(5H)-one.
4-Hydroxy-1H-pyrrol-2(5H)-one (CAS 503-83-3) is a high-purity analytical reference standard with the molecular formula C4H5NO2 and a molecular weight of 99.09 g/mol.
The molecular framework of 4-Hydroxy-1H-pyrrol-2(5H)-one (C4H5NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Hydroxy-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H5NO2 |
| Molecular Weight | 99.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 3-Hydroxy-1H-pyrrol-2(5H)-one (CAS 693826-68-5)
- 5-Hydroxy-1H-pyrrol-3(2H)-one (CAS 79469-69-5)
- 3-Hydroxy-3-methylbutyronitrile (CAS 13635-04-6)
- 2-Hydroxy-3-methylbutanenitrile (CAS 15344-34-0)
- 3-Hydroxy-2,2-dimethylpropanenitrile (CAS 19295-57-9)
- 2-Hydroxy-2-methylbutanenitrile (CAS 4111-08-4)
- 3-Hydroxy-2-methylbutanenitrile (CAS 38046-46-7)
- 4-Hydroxy-3-methylbutanenitrile (CAS 64404-55-3)
Recommended Standards
- 4-amino-2,5-dihydro-1H-imidazol-2-one (CAS 61318-63-6)
- 4-Methoxyisoxazole (CAS 83259-38-5)
- 4-Amino-1H-pyrazol-3(2H)-one (CAS 90293-76-8)
- 4-Methyl-1H-1,2,4-triazol-5(4H)-one (CAS 4114-43-6)
- 6-Hydroxy-2-phenyltetrahydro-1H-pyrrolo[1,2-c]imidazole-1,3(2H)-dione (CAS 321391-92-8)
- 5,8-Difluoro-4,4-dimethyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-24-9)
- (S)-tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate (CAS 142253-50-7)
- (R)-2-Amino-2-carboxyethylmethanethiosulfonate (CAS 351422-29-2)
- (R)-1-(Quinolin-6-yl)ethan-1-ol (CAS 1344951-96-7)
- 1,1-Dioxido-2,3-dihydro-4H-thieno[2,3-b]thiopyran-4-yl 3-methoxybenzoate (CAS 343373-78-4)
- (5-Methyl-1,3,4-thiadiazol-2-yl)methanol (CAS 869108-51-0)
- Bempedoic Acid Intermediate Impurity 14 d4 (CAS 2408132-01-2)
- (3,5-Dichlorophenyl)(4-ethoxyphenyl)methanone (CAS 951884-70-1)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com