3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one CAS 503111-24-8

Purity 97%+In StockPharmaceutical Standards
CAS No.503111-24-8
Molecular FormulaC7H10F3NO3
Molecular Weight213.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one CAS 503111-24-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one.

3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one (CAS 503111-24-8) is a high-purity analytical reference standard with the molecular formula C7H10F3NO3 and a molecular weight of 213.15 g/mol.

The molecular framework of 3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one (C7H10F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Ethoxy-5-hydroxy-5-(trifluoromethyl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H10F3NO3
Molecular Weight213.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms1

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