1-[2-methoxy-5-(trifluoromethyl)phenyl]ethanone CAS 503464-99-1
| CAS No. | 503464-99-1 |
| Molecular Formula | C10H15F3O2 |
| Molecular Weight | 224.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[2-methoxy-5-(trifluoromethyl)phenyl]ethanone (C10H15F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-[2-methoxy-5-(trifluoromethyl)phenyl]ethanone (CAS 503464-99-1) is a high-purity analytical reference standard with the molecular formula C10H15F3O2 and a molecular weight of 224.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[2-methoxy-5-(trifluoromethyl)phenyl]ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15F3O2 |
| Molecular Weight | 224.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
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Recommended Standards
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- 2-(6-(Benzyloxy)hexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2030409-63-1)
- 6-Chloro-3-(3-chlorophenyl)[1,2,4]triazolo[4,3-b]pyridazine (CAS 56383-51-8)
- 1-(1-Benzylpyrrolidin-3-yl)-1H-pyrazol-5-amine (CAS 1152544-66-5)
- 2-(2-Cyclohexylethoxy)-4-methylaniline (CAS 946683-20-1)
- 2-Methyl-3-furanthiol acetate 2-Methyl-3-furyl thioacetate 2-Methylfuran-3-thioacetate 3-(Acetylthio)-2-methylfuran 55764-25-5 Ethanethioic acid, S-(2-methyl-3-furanyl) ester MFT Acetate S-(2-methyl-3-furyl) ethanethioate (CAS 55764-25-5)
- 1-(3-Benzhydryl-5-methylisoxazol-4-yl)ethanone (CAS 77854-04-7)
- H-cis-4-Fluoro-Pro-OH (CAS 2438-57-5)
- 2-(4-Chloro-3-methyl-phenoxy)-butyric acid (CAS 1006483-33-5)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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