Tiapride Hydrochloride EP Impurity B CAS 50390-76-6
| CAS No. | 50390-76-6 |
| Molecular Formula | C9H10O5S |
| Molecular Weight | 230.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tiapride Hydrochloride EP Impurity B is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Tiapride Hydrochloride EP Impurity B (CAS 50390-76-6), a pharmacopoeial impurity reference standard (molecular formula C9H10O5S, MW 230.24 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tiapride Hydrochloride EP Impurity B (C9H10O5S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10O5S |
| Molecular Weight | 230.24 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Sulfur Atoms | 1 |
Related Tiapride Standards
- Tiapride EP Impurity A (CAS 63484-12-8)
- Tiapride impurity 07 (CAS 2969375-71-9)
- Tiapride impurity 9 (CAS CATO-C4X-23009)
- Tiapride Impurity 2 (CAS 98517-73-8)
- Tiapride (CAS 51012-32-9)
- Tiapride EP Impurity D (CAS 63484-11-7)
- Tiapride Impurity 3 HCl (CAS CATO-C4X-23003)
- Tiapride hydrochloride (CAS 51012-33-0)
Recommended Standards
- Sulpiride EP Impurity E (CAS 52395-25-2)
- Ethoxydiphenylphosphine (CAS 719-80-2)
- Cefcapene Impurity 86 (CAS 2165460-37-5)
- Asulam (CAS 3337-71-1)
- Sarpogrelate Impurity 18 (CAS 1659311-47-3(free base))
- Lenalidomide Impurity 48 (CAS CATO-C4X-190348)
- Cholic Acid Impurity 13 (CAS 2304-92-9)
- n-(2,3-Dimethylbenzyl)cyclopentanamine (CAS 1184286-32-5)
- 2-((2-Aminoethyl)(6-((5-cyanopyrazin-2-yl)amino)pyrimidin-4-yl)amino)acetamide (CAS 1137475-09-2)
- 6-(4-Chlorophenyl)-2-methylnicotinic acid (CAS 912617-77-7)
- 2-Cyano-3-(4-fluorophenyl)propiophenone (CAS 898767-96-9)
- Ruthenium(2+), bis(acetonitrile)bis[1,3-dihydro-1-(2-pyridinyl-κN)-3-(2,4,6-trimethylphenyl)-2H-imidazol-2-ylidene-κC]-, (OC-6-33)-, hexafluorophosphate(1-) (1:2) (CAS 2088512-45-0)
- tert-Butyl 4-(5-((6-chloro-4-(methoxycarbonyl)pyridin-2-yl)oxy)pyrimidin-2-yl)piperazine-1-carboxylate (CAS 2007908-94-1)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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