7-Cyano-2-naphthoic acid CAS 5043-08-3
| CAS No. | 5043-08-3 |
| Molecular Formula | C12H7NO2 |
| Molecular Weight | 197.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Cyano-2-naphthoic acid (CAS 5043-08-3) is a high-purity analytical reference standard with the molecular formula C12H7NO2 and a molecular weight of 197.19 g/mol.
7-Cyano-2-naphthoic acid (C12H7NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Cyano-2-naphthoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7NO2 |
| Molecular Weight | 197.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Cyano Standards
- 3-Cyano-2-naphthoic acid (CAS 858022-47-6)
- 4-Cyano-1-naphthoic acid (CAS 3839-19-8)
- 5-Cyano-2-naphthoic acid (CAS 5043-32-3)
- 6-Cyano-2-naphthoic Acid (CAS 5159-60-4)
- 5-Cyano-N-methylpyridine-2-sulfonamide (CAS 1334493-79-6)
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Recommended Standards
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