Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate CAS 505053-94-1
| CAS No. | 505053-94-1 |
| Molecular Formula | C12H9F3N2O2S2 |
| Molecular Weight | 334.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate (C12H9F3N2O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate (CAS 505053-94-1), a certified reference material (molecular formula C12H9F3N2O2S2, MW 334.34 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O2S2 |
| Molecular Weight | 334.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methyl Standards
- Methyl 2-((3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanoate (CAS 868967-05-9)
- N-(2-(2-(Thiophen-2-yl)thiazolo[3,2-b][1,2,4]triazol-6-yl)ethyl)pivalamide (CAS 941999-56-0)
- N-(2-(Thiophen-3-yl)benzyl)benzofuran-2-carboxamide (CAS 1797713-29-1)
- (3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl)methyl 2-(methylthio)nicotinate (CAS 924179-93-1)
- 2-(4-Oxo-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-3-yl)ethane-1-sulfonic acid (CAS 324564-39-8)
- Ethyl 2-(2-(thiophen-2-yl)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (CAS 746607-75-0)
- 1-((4-Methyl-2-(thiophen-2-yl)thiazol-5-yl)methyl)-3-(thiophen-2-yl)urea (CAS 1396814-79-1)
- 3-(Thiophen-2-yl)-1-(7-(thiophen-2-yl)-1,4-thiazepan-4-yl)prop-2-en-1-one (CAS 1706516-12-2)
Recommended Standards
- Ethyl 5-[4-(trifluoromethyl)phenylthio]-1,2,3-thiadiazole-4-carboxylate (CAS 338982-06-2)
- N-(4-(pyrrolidin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 251097-28-6)
- Ethyl 5-((3-(trifluoromethyl)phenyl)thio)-1,2,3-thiadiazole-4-carboxylate (CAS 306977-11-7)
- N-(6-ethoxybenzo[d]thiazol-2-yl)-2,6-difluorobenzamide (CAS 476277-40-4)
- 1-(Tert-butyl) 2-methyl (2S,4S)-4-(3-bromo-4-formylphenoxy)pyrrolidine-1,2-dicarboxylate (CAS 2442510-71-4)
- 3-(4-Chlorophenyl)-8-isopropyl-1,4,8-triazaspiro[4.5]Dec-3-ene-2-thione (CAS 1325305-00-7)
- 4-Bromo-1-(3,4-difluorophenyl)-1H-pyrazole (CAS 1353856-07-1)
- 4-Chloro-2-fluoro-5-methylbenzoic acid (CAS 177211-31-3)
- (E)-5-styryl-1H-pyrazole-4-carbaldehyde (CAS 1159834-02-2)
- (4-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)methanamine (CAS 1211596-38-1)
- [1-benzothiophen-3-yl(pyridin-3-yl)methyl](ethyl)amine (CAS 1154227-93-6)
- 3-(Bromodifluoromethyl)-5-phenyl-1H-pyrazole (CAS 1355046-54-6)
- 4-(2-Acetamidoethyl)-3-iodobenzoic acid (CAS 1131622-45-1)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com