6-(2-Fluorophenyl)nicotinic Acid CAS 505082-91-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(2-Fluorophenyl)nicotinic Acid.

6-(2-Fluorophenyl)nicotinic Acid (CAS 505082-91-7) is a high-purity analytical reference standard with the molecular formula C12H8FNO2 and a molecular weight of 217.20 g/mol.

6-(2-Fluorophenyl)nicotinic Acid (C12H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(2-Fluorophenyl)nicotinic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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