(+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376 CAS 50622-09-8

Purity 97%+In StockPharmaceutical Standards
CAS No.50622-09-8
Molecular FormulaC7H14O4
Molecular Weight162.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376 CAS 50622-09-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376.

(+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376 (CAS 50622-09-8) is a high-purity analytical reference standard with the molecular formula C7H14O4 and a molecular weight of 162.18 g/mol.

(+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376 (C7H14O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (+)-2,3-O-Isopropylidene-L-threitol (4S,5S)-(+)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol (4S,5S)-(+)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane 50622-09-8 I0376 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H14O4
Molecular Weight162.18 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1971

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