Thioctic acid Impurity 33 CAS 50628-92-7

Description

Compared with other compounds in its class, the molecular weight of 184.23 g/mol gives Thioctic acid Impurity 33 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Thioctic acid Impurity 33 (CAS 50628-92-7) is a certified pharmaceutical impurity reference standard with the molecular formula C10H16O3 and a molecular weight of 184.23 g/mol.

Thioctic acid Impurity 33 (C10H16O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Thioctic acid Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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