2-(Chloromethyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole CAS 50677-30-0
| CAS No. | 50677-30-0 |
| Molecular Formula | C9H6ClN3O3 |
| Molecular Weight | 239.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Chloromethyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole (CAS 50677-30-0), a certified reference material (molecular formula C9H6ClN3O3, MW 239.62 g/mol) for analytical method development and quality control.
2-(Chloromethyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole (C9H6ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Chloromethyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClN3O3 |
| Molecular Weight | 239.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloromethyl Standards
- 5-Chloromethyl-1-(4-nitro-phenyl)-1H-tetrazole (CAS 107269-72-7)
- 2-ChloroMethyl-3-Methyl-4-trifluoroethylpyridine (CAS 128430-66-0)
- 2-(chloromethyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole (CAS 63002-55-1)
- 2-(Chloromethyl)-5-(3-nitrophenyl)-1,3,4-oxadiazole (CAS 63002-57-3)
- 5-(Chloromethyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 6595-78-4)
- 5-(Chloromethyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole (CAS 57611-19-5)
- (4E)-3-(Chloromethyl)-4-(2-fluorobenzylidene)-isoxazol-5(4H)-one (CAS 1142199-21-0)
- (E)-3-(chloromethyl)-4-(4-fluorobenzylidene)isoxazol-5(4H)-one (CAS 1142199-23-2)
Recommended Standards
- 3-((3-Chlorophenyl)amino)-1,1,1-trifluoropropan-2-ol (CAS 370-38-7)
- 3-(4-Chloro-3-nitrophenyl)-5-methyl-1,2,4-oxadiazole (CAS 92453-47-9)
- 2-(3-Chlorophenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886763-82-2)
- 3-CHloro-2-(propan-2-yloxy)-5-(trifluoromethyl)pyridine (CAS 750608-07-2)
- Ethyl 4-amino-2-chloro-6-methylpyrimidine-5-carboxylate (CAS 43106-78-1)
- (S)-2-(Methyl(1-methylpyrrolidin-3-yl)amino)ethanol (CAS 1354000-22-8)
- 4-Methyl-5-[(4-pentylcyclohexyl)methyl]-4H-1,2,4-triazole-3-thiol (CAS 866132-83-4)
- N-Cyclopropyl-3-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 585544-29-2)
- 5-Methylquinolin-6-ol (CAS 76915-90-7)
- 4-Methyl-5-nitropyridine-2-thiol (CAS 25391-79-1)
- 4-(Aminomethyl)-3-(difluoromethyl)-5-methylpyridin-2-ol (CAS 1805449-86-8)
- 2-Amino-7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one (CAS 61938-75-8)
- 2,3-Difluoro-4-methylbenzodifluoride (CAS 1803851-65-1)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com