Vortioxetine Impurity 120 HCl CAS 508233-76-9(free base)
| CAS No. | 508233-76-9(free base) |
| Molecular Formula | C18H22N2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Vortioxetine Impurity 120 HCl (CAS 508233-76-9(free base)), a pharmacopoeial impurity reference standard (molecular formula C18H22N2SHCl, MW 334.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Vortioxetine Impurity 120 HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 334.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22N2S HCl |
| Molecular Weight | 334.91 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Vortioxetine Standards
- Vortioxetine Impurity 63 (CAS 1009-85-4)
- Vortioxetine Impurity 2 (CAS 1011-13-8)
- Vortioxetine Impurity 89 (CAS 1019453-85-0)
- Vortioxetine Impurity 116 (CAS 102439-46-3)
- Vortioxetine Impurity 88 (CAS 103-19-5)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 48 (CAS 105456-67-5)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
Recommended Standards
- Terbutaline Impurity 74 HCl (CAS CATO-C4X-118374)
- Irinotecan Impurity 22 (CAS 124622-81-7)
- Methylergometrine EP Impurity I Acetate (CAS 724767-21-9 (free base))
- N'-[(1E)-[6-(4-Bromophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylidene]-4-(trifluoromethyl)benzohydrazide (CAS 691887-87-3)
- 4-Bromo-2-tert-butylaniline (CAS 850012-44-1)
- 2-((4-Methylcyclohexyl)oxy)acetic acid (CAS 855933-50-5)
- (E)-[(4-Chlorophenyl)methoxy]({5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methylidene)amine (CAS 321533-78-2)
- 3-(1h-Indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-4-ol (CAS 736949-28-3)
- 4-Methoxy-3-[(3-nitrophenoxy)methyl]benzaldehyde (CAS 832741-11-4)
- Peptide Impurity 28 (CAS 1350456-64-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com