2-Hydroxy-2-phenylacetyl chloride CAS 50916-31-9
| CAS No. | 50916-31-9 |
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Hydroxy-2-phenylacetyl chloride.
2-Hydroxy-2-phenylacetyl chloride (CAS 50916-31-9), molecular formula C8H7ClO2 and molecular weight 170.59 g/mol, is a CATO reference standard with documented purity and traceability.
2-Hydroxy-2-phenylacetyl chloride (C8H7ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Hydroxy-2-phenylacetyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
Related Hydroxy Standards
- 4-Hydroxy-3-methylbenzoyl chloride (CAS 1099832-26-4)
- 2-Hydroxy-6-methylbenzoyl chloride (CAS 1261649-90-4)
- 3-Hydroxy-5-methylbenzoyl chloride (CAS 1261679-27-9)
- 1-(4-Hydroxy-2-chlorophenyl)ethanone (CAS 68301-59-7)
- 2-Hydroxy-5-isopropyl-benzaldehyde (CAS 90564-23-1)
- 2-Hydroxy-5-methylbenzoyl chloride (CAS 41081-61-2)
- 3-Hydroxy-4-methylbenzoyl chloride (CAS 348165-48-0)
- N-Hydroxy-(5-methylpyridine)-2-carbonimidoyl chloride (CAS 1009562-90-6)
Recommended Standards
- 2-Chloro-6-methylbenzoic acid, 97% (CAS 21327-86-6)
- 2-Chloro-6-methoxybenzaldehyde (CAS 29866-54-4)
- 2-Chloro-5-methylbenzoic Acid (CAS 6342-60-5)
- 3-(Chloromethyl)-4-hydroxybenzaldehyde (CAS 53412-47-8)
- N1-(3,4-Dimethylphenyl)-N2-(1-hydroxybutan-2-yl)oxalamide (CAS 920360-80-1)
- 5-methylpyrimidin-2-amine (CAS 50840-23-8)
- 2-(3-(Dimethylamino)propoxy)-3-methoxybenzaldehyde hydrochloride (CAS 1049696-06-1)
- 7-Chloro-4-hydrazinyl-2-methylquinoline hydrochloride (CAS 1172414-66-2)
- Chloranthalactone E (CAS 73215-92-6)
- 4-Penten-1-ol (CAS 821-09-0)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
- (2E)-1-(4-Ethoxyphenyl)-3-(3-fluorophenyl)prop-2-en-1-one (CAS 1287402-67-8)
- Methyl 3-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoate (CAS 1005583-79-8)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com