5-Chloro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid CAS 511231-71-3
| CAS No. | 511231-71-3 |
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 211.64 g/mol gives 5-Chloro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (CAS 511231-71-3) is a high-purity analytical reference standard with the molecular formula C10H10ClNO2 and a molecular weight of 211.64 g/mol.
5-Chloro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (C10H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO2 |
| Molecular Weight | 211.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-chloro-1-(difluoromethyl)pyrazolo[4,3-b]pyridine (CAS 2468028-32-0)
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- PNU 142633 (CAS 187665-65-2)
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- (1R,2S,3R,4S)-1,4-diamino-5-chloro-1,2,3,4-tetrahydronaphthalene-2,3-diol (CAS 1998128-34-9)
- N-(5-Bromo-2-methylphenyl)acrylamide (CAS 1154729-31-3)
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- 2-(6-Bromo-3-(difluoromethyl)-5-methylpyridin-2-yl)acetonitrile (CAS 1804851-02-2)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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