(2-nitrophenyl)methanesulfonamide CAS 51145-00-7

Description

Compared with other compounds in its class, the molecular weight of 216.21 g/mol gives (2-nitrophenyl)methanesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2-nitrophenyl)methanesulfonamide (CAS 51145-00-7) is a high-purity analytical reference standard with the molecular formula C7H8N2O4S and a molecular weight of 216.21 g/mol.

The molecular framework of (2-nitrophenyl)methanesulfonamide (C7H8N2O4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2-nitrophenyl)methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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