Ethyl 2-hydroxy-6-methylnicotinate CAS 51146-04-4
| CAS No. | 51146-04-4 |
| Molecular Formula | C9H11NO3 |
| Molecular Weight | 181.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-hydroxy-6-methylnicotinate.
CATO supplies Ethyl 2-hydroxy-6-methylnicotinate (CAS 51146-04-4), a certified reference material (molecular formula C9H11NO3, MW 181.19 g/mol) for analytical method development and quality control.
Structurally, Ethyl 2-hydroxy-6-methylnicotinate (C9H11NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 181.19 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11NO3 |
| Molecular Weight | 181.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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- 2-Hydroxy-6-methoxy-N-methylbenzamide (CAS 1056956-21-8)
- N-Hydroxy-2-methoxy-6-methylisonicotinimidamide (CAS 1122091-74-0)
- Methyl 2-hydroxy-3-(pyridin-2-yl)propanoate (CAS 1181631-91-3)
- 3-Hydroxy-2-methoxy-N-methylbenzamide (CAS 1190090-16-4)
- 4-Hydroxy-2-methoxy-N-methylbenzamide (CAS 1190090-24-4)
- 3-Hydroxy-4-methoxy-N-methylbenzamide (CAS 1243280-60-5)
Recommended Standards
- Ethyl 2-hydroxy-5-methylnicotinate (CAS 85147-15-5)
- Ethyl 2-methyl-4-oxo-1,4-dihydropyridine-3-carboxylate (CAS 260389-91-1)
- Ethyl 2-hydrazinylisonicotinate (CAS 90090-94-1)
- Ethyl 2-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 3424-43-9)
- 1H-Benzoimidazole-2-thiol (CAS 134469-07-1)
- 2,7-Bis(2-aminoethoxy)-9H-fluoren-9-one (CAS 861122-44-3)
- 3-(2,4-Dichlorophenyl)-1-methyl-1h-pyrazol-5-amine (CAS 133113-09-4)
- 1-Chloro-7-nitropyrrolo[1,2-a]pyrazine (CAS 1053656-45-3)
- Ethyl [2,3'-bipyridine]-3-carboxylate (CAS 1214336-58-9)
- 1,2-Dichloro-3-(trifluoromethoxy)benzene (CAS 151276-09-4)
- 5-Ethoxycarbonylamino-[1,2,3]thiadiazole-4-carboxylic acid ethyl ester (CAS 2037-78-7)
- 3-Amino-4-ethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxylic acid (CAS 761444-34-2)
- 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5 (CAS 453-72-5)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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